Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0003rdr32 | Environmental and Metabolic Interactions | REDR1994

Melatonin binding sites and their role in seasonal reproduction

Kennaway DJ , Rowe SA

The pineal gland has a major role in the translation of scotophase duration into a hormonal signal by the hormone melatonin. Animals such as sheep, goats and deer use the seasonal variation of this signal to coordinate reproductive behaviour with the environment. Despite intensive research over more than 30 years the site(s) of action of melatonin and the resultant intracellular responses are still not clear. This review discusses recent work that has localized the site of act...

bp0001redr2 | (1) | REDR1980

The role of the pineal gland in seasonality

Seamark RF , Kennaway DJ , Matthews CD , Fellenberg AJ , Phillipou G , Kotaras P , McIntosh JEA , Dunstan E , Obst JM

Summary. The life time reproductive performance of 2 flocks of Merino crossbred ewes pinealectomized at 7–60 days of age, and maintained in South Australia did not differ from that of sham-operated control animals kept in the same flocks. The pineal gland is therefore not a major determinant of reproductive success, but a role for the pineal in adjusting breeding activity to season is not excluded. It was confirmed that pineal denervation of adult ewes ...